{"id":361,"date":"2020-01-31T08:31:54","date_gmt":"2020-01-31T14:31:54","guid":{"rendered":"http:\/\/www.nano-blog.com\/?p=361"},"modified":"2022-09-02T14:12:24","modified_gmt":"2022-09-02T19:12:24","slug":"is-that-all-there-is","status":"publish","type":"post","link":"http:\/\/www.nano-blog.com\/?p=361","title":{"rendered":"Is that all there is?"},"content":{"rendered":"\n<p>With apologies for using the title of a Peggy Lee song from\nthe 70s, this reference is to nanotechnology.&nbsp;\nThere are continually more interesting findings as researchers move into\nsmaller and smaller particle sizes.&nbsp; The question\nreally is what happens when the ability to work at sizes as single digit\nnanometer particles and smaller becomes practical. &nbsp;To some extent, research is already at this\npoint.&nbsp; What new properties will become\nknown?<\/p>\n\n\n\n<p>There has been concern that the absorption of heave metals\ncan have a detrimental effect on the human body by becoming a cumulative toxic.&nbsp; Gold nanoparticles have been employed in\nvarious cancer cure Efforts since the early 2000s.&nbsp; A recent report [Ref. 1] indicates that gold,\nchemically inert, does not remain intact within cellular structures.&nbsp; In work done by researchers at the University\nof Paris, Sorbonne University, and the University of Strasbourg has revealed\nthat gold nanoparticles ranging from 4nm to 22nm indicates these particles do\nnot remain unchanged.&nbsp; &nbsp;&nbsp;They observed a transformation of the\nnanoparticles into leaf shaped structures.&nbsp;\nThese finding may provide additional avenues of investigation for\ndetermining the means which the human body metabolizes the particles.&nbsp; This could change the overall evaluation of\npotential toxicity.<\/p>\n\n\n\n<p>As mentioned in last month\u2019s blog, researchers have been\nable to strengthen the structure of silver without diminishing it conductive\nproperties by \u201cimplanting\u201d copper atoms at defect along the grain boundaries of\nthe silver.&nbsp; The maximum strengthening\nappears to occur when the grain boundaries are 7nm apart. [Ref. 2]<\/p>\n\n\n\n<p>There has been a number of articles on two-dimensional materials,\nlike graphene.&nbsp; An article in Nature\nElectronics [Ref. 3] describes the development of heterostructures form by\nstacking layers of different two-dimensional materials that are possible due to\nVan der Waals forces.&nbsp; This particular\napplication create memristors with good thermal stability.&nbsp; <\/p>\n\n\n\n<p>This bring the discussion to the progress in Atomically\nPrecise Manufacturing (APM).&nbsp; From\nWikipedia, \u201c<em>APM is the production of materials, structures, devices, and\nfinished goods in a manner such that every atom has a specific location\nrelative to the other atoms <\/em>\u2026\u201d [Ref. 4]&nbsp;\nIn 2017, the American Chemical Society has a report [Ref. 5] that indicates\nover 100 molecules of noble metals have been created and are able to de\nmanufactured.&nbsp; The molecules demonstrate\ndifferent properties that are different from the nanomaterials.&nbsp; The research effort has grown to the point\nwhere there is a conference on Atomically Precise Nanochemistry. [Ref. 6]<\/p>\n\n\n\n<p>So, Nanotechnology is not the bottom.\u00a0 There is also work being on electron spin in the quantum realm.\u00a0 The one consideration that needs to move forward as the APM and other atomic level research progresses in the issue of \u201csafety\u201d.\u00a0 \u00a0The development of a \u201cwhite\u201d paper on the challenges for the manufacture, storage, and handling of these even smaller particles has been initiated with the anticipated release of the recommendation late in 2020.\u00a0 This effort will be a complementary effort to the existing Nano-Safety \u201cwhite\u201d paper from 2007. [Ref. 7]<\/p>\n\n\n\n<p><strong>References:<\/strong><\/p>\n\n\n\n<ol class=\"wp-block-list\"><li><strong><a href=\"https:\/\/physicsworld.com\/a\/gold-nanoparticles-inside-cells-are-not-inert-say-researchers\/?utm_medium=email&amp;utm_source=iop&amp;utm_term=&amp;utm_campaign=14290-45008&amp;utm_content=Title%3A%20Gold%20nanoparticles%20inside%20cells%20are%20not%20inert%2C%20say%20researchers%20%20-%20Editors_pick&amp;Campaign+Owner=\">https:\/\/physicsworld.com\/a\/gold-nanoparticles-inside-cells-are-not-inert-say-researchers\/?utm_medium=email&amp;utm_source=iop&amp;utm_term=&amp;utm_campaign=14290-45008&amp;utm_content=Title%3A%20Gold%20nanoparticles%20inside%20cells%20are%20not%20inert%2C%20say%20researchers%20%20-%20Editors_pick&amp;Campaign+Owner=<\/a><\/strong><\/li><li><strong><a href=\"https:\/\/www.uvm.edu\/uvmnews\/news\/inventing-worlds-strongest-silver\">https:\/\/www.uvm.edu\/uvmnews\/news\/inventing-worlds-strongest-silver<\/a><\/strong><strong>&nbsp; <\/strong><\/li><li><strong><a href=\"https:\/\/www.nature.com\/articles\/s41928-018-0021-4\">https:\/\/www.nature.com\/articles\/s41928-018-0021-4<\/a>\n<\/strong><\/li><li><strong><a href=\"https:\/\/en.wikipedia.org\/wiki\/Atomically_precise_manufacturing\">https:\/\/en.wikipedia.org\/wiki\/Atomically_precise_manufacturing<\/a><\/strong><\/li><li><strong><a href=\"https:\/\/pubs.acs.org\/doi\/abs\/10.1021\/acs.chemrev.6b00769\">https:\/\/pubs.acs.org\/doi\/abs\/10.1021\/acs.chemrev.6b00769<\/a><\/strong><\/li><li><strong><a href=\"https:\/\/www.grc.org\/atomically-precise-nanochemistry-conference\/2020\/\">https:\/\/www.grc.org\/atomically-precise-nanochemistry-conference\/2020\/<\/a>\n<\/strong><\/li><li><strong><a href=\"http:\/\/www.tryb.org\/a_white_paper_on_nano-safety.pdf\">http:\/\/www.tryb.org\/a_white_paper_on_nano-safety.pdf<\/a>\n<\/strong><\/li><\/ol>\n","protected":false},"excerpt":{"rendered":"<p>With apologies for using the title of a Peggy Lee song from the 70s, this reference is to nanotechnology.&nbsp; There are continually more interesting findings as researchers move [..]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[14,9],"tags":[],"class_list":["post-361","post","type-post","status-publish","format-standard","hentry","category-misc-ramblings","category-nano"],"_links":{"self":[{"href":"http:\/\/www.nano-blog.com\/index.php?rest_route=\/wp\/v2\/posts\/361","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/www.nano-blog.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.nano-blog.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.nano-blog.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.nano-blog.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=361"}],"version-history":[{"count":1,"href":"http:\/\/www.nano-blog.com\/index.php?rest_route=\/wp\/v2\/posts\/361\/revisions"}],"predecessor-version":[{"id":362,"href":"http:\/\/www.nano-blog.com\/index.php?rest_route=\/wp\/v2\/posts\/361\/revisions\/362"}],"wp:attachment":[{"href":"http:\/\/www.nano-blog.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=361"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.nano-blog.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=361"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.nano-blog.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=361"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}